Australia pick up seven-wicket, South Africa take the series 2-1 after conceding the day-night Test to a new-look Australian side.
South Africa lead by 70 with four wickets in hand after Australia dismissed for 383.
Usman Khawaja posted the most important century of his cricket career to help takes a 48-run lead against South Africa on the second day Friday of the day-night test.
Australia are playing at 0-14 trailing by 245 at the end of Day One at Adelaide Oval on Thursday.
Australia look to avoid their first ever home Test series whitewash against rampant South Africa.
Crisis-hit Australia included English-born opener Matt Renshaw among six changes to their revamped Test squad Sunday.
South Africa dismissed Australia for 161 to win the second test by an innings and 80 runs before lunch on day four at Bellerive Oval on Tuesday.
At stumps on the third day the home side were hanging in at two for 121, still 120 runs behind the South Africa.
Rail force play was abandoned on the second day of the second Test between Australia and South Africa without a ball being bowled.
South Africa were five for 171 at the close after skittling Australia for 85 on the opening day of the second Test in Hobart on Saturday.