Hong Kong were bundled out on a paltry score of 38 runs. Pakistan face India on Sunday in Super 4.
India outplayed Hong Kong in all departments and also became the second team to qualify for the Super four.
Oman qualifies for ICC T20 World Cup 2020.
From 174-0, Hong Kong lost their way and huffed and puffed past the 250-run mark, eventually India won by 26 runs.
Hong Kong will look to raise their game against defending champions India in Dubai on Tuesday.
Pakistan starts the tournament with a thumping 8 wicket win over Hong Kong in Dubai on Sunday.