England 281 (Duckett 63, Pope 60, Abrar 7-114) and 275 (Brook 108, Duckett 79, Abrar 4-120) beat Pakistan 202 (Babar 75, Shakeel 63, Leach 4-98) and 328 (Shakeel 94, Imam 60, Wood 4-65) by 26 runs
Multan: England pulled off another sensational victory in Pakistan, winning the second Test by 26 runs to seal a historic series triumph.
Mark Wood took three crucial wickets on the fourth day in Multan just as Pakistan were closing in on what would have been a superb chase of 355.
His efforts secured victory for England in their first Test series in Pakistan since 2005 and their first over these opponents outside of the UK in 22 years.
At 290-5, Wood had Mohammad Nawaz caught down the leg side for 45 then, one run later, did the same to dismiss Saud Shakeel for 94, but only after a lengthy deliberation by the third umpire.
Abrar Ahmed was caught at cover off James Anderson and Wood splattered the stumps of Zahid Mahmood at pace in excess of 90mph for his fourth wicket of the innings.
Though Salman Agha kept tension high with regular boundaries, Ollie Robinson had number 11 Mohammad Ali caught behind to leave Pakistan 328 all out.
This is also the first time England have ever won two Tests in an away series against Pakistan.
They will look for a clean sweep in the third and final Test in Karachi, which begins on Saturday.