Dublin: Kevin O'Brien and Paul Stirling will both be fit for Ireland's first-ever one-day internationals against England on English soil on 5 and 7 May.
O'Brien has recovered from a hamstring injury which saw him miss three of the five ODIs against Afghanistan in March.
Stirling is named in a 14-man squad following a finger injury sustained during the Intercontinental Cup game with the Afghans on the same tour.
Boyd Rankin and Jacob Mulder will miss the matches because of back injuries.
Warwickshire bowler Rankin, 32, returned to his national side last year after a brief and unfulfilling switch to England, which culminated in a single Test appearance against Australia.
O'Brien famously scored the fastest century in World Cup history as Ireland secured a three-wicket win over England in 2011.
Ireland will face England at Bristol in the first of the two games and the teams will meet again at Lord's two days later.
Ireland have previously played five home ODIs against England and two in global tournaments,
Ireland squad for England ODI series: