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London: Australia will head to Old Trafford with a 2-0 lead in this series after their 64-run win over England at Lord's on Saturday.
Midway through England's reply, Ben Stokes was given out after the ball hit his hand as he took evasive action.
Steve Smith struck 70 and Mitchell Marsh 64 from 31 balls as Australia made 309-7 from their 49 overs.
Skipper Eoin Morgan fired four sixes in a defiant 85 but England were all out for 245 to lose by 64 runs.
It was only the sixth dismissal for obstructing the field in the 3,861-match history of one-day internationals and the first for an England player.
In the 26th over, Stokes pushed a defensive shot back at bowler Mitchell Starc, who hurled the ball back at the batsman as he saw him leave his crease and sensed the chance of a run-out.
Stokes turned away as the throw arrowed towards both him and the stumps and dived back in an attempt to regain his ground, but the ball hit his outstretched hand.
On-field umpires Kumar Dharmasena and Tim Robinson consulted third umpire Joel Wilson who applied law 33.1, deeming that Stokes had "wilfully" obstructed the field.
The third of the five matches takes place at Old Trafford on Tuesday.
Brief scores
Australia - 309/7 (Smith 70, Marsh 64, Bailey 54, Stokes 3-60)
England - 245 (Morgan 85, Cummins 4-56)
Result - Australia won by 64 runs
